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ARDANA SECURES FULL GLOBAL RIGHTS TO LONG ACTING GNRH ANTAGONIST FROM ZENTARIS

Ardana Bioscience, the specialty pharmaceutical company dedicated to better reproductive health, has acquired full global rights to the Gonadotrophin releasing hormone (GnRH)-antagonist, Teverelix, which has the potential to treat prostate cancer, endometriosis and benign prostate hyperplasia, from the biopharmaceutical company Zentaris, a wholly owned subsidiary of Aeterna Laboratories Inc (NASDAQ:AELA;TSX:AEL). In return, Zentaris receives a series of undisclosed payments on signature, during the remainder of product development and on attainment of certain milestones and sales.

Under the terms of the agreement, Ardana has acquired all outstanding territorial rights to Teverelix (Japan, Korea and Taiwan) and is assigned the intellectual property relating to the drug and the underlying microcrystalline suspension technology on a worldwide basis. Ardana acquired all other territorial rights to Teverelix in July 2002. As part of the agreement Zentaris will continue to provide certain development services for and supply clinical samples to Ardana. Phase I trials with a sustained release formulation of Teverelix are nearing conclusion.

Dr Maureen Lindsay, Ardana Chief Operating Officer said: We are delighted to have secured all global rights to Teverelix, such that we can reap the full benefits of its development and commercialization. Our strategy is to focus on drugs prescribed by specialist clinicians, a market we can service effectively with our planned specialist sales force. Teverelix fits neatly into this strategy and is central to our burgeoning research and development portfolio, which is on track to provide products which address five different indications in Phase III clinical trials by the end of 2005.

Professor Dr Juergen Engel, Chairman and Managing Director of Zentaris GmbH and Chief Operating Officer of Aeterna commented: We are delighted to extend our existing relationship with Ardana. It emphasizes the commitment of Ardana to the successful development of Teverelix and allows for Zentaris to benefit from the commercialization of the product.

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